Reading and Writing the Future of Antibodies

Writing the Future of Biologics using the Twist Biopharma Library of Libraries and LoopSeq Long-read Amplicon Sequencing

Date & Time

June 23, 2021 | 9 am PDT (6pm CEST)

Webinar Description

Twist Biopharma’s unique DNA writing technology enables the printing of DNA pools with unparalleled diversity and precision coupled with game-changing throughput and quality. Together with Loop Genomics and their synthetic long-read technologies for NGS, Twist Biopharma can further increase their speed, combined with additional innovative approaches for antibody discovery and engineering.


In this webinar, you will learn how:

  • Twist Biopharma, a division of Twist Bioscience, leverages the use of LoopSeq long-read PCR amplicon sequencing of synthetic and semi-synthetic phage-displayed antibody libraries. 
  • LoopSeq technology delivers fully assembled contigs, further enabling full characterization of antibody diversity in each panning round without the time and reagent costs of isolating clonal variants. 
  • Along with amplicon abundance data, we can track enrichment of each antibody variant through the panning rounds. 
  • Twist Biopharma has fully integrated the LoopSeq sequencing platform into multiple antibody discovery campaigns using VHH, scFv, and Fab-based libraries to identify high-affinity monoclonal antibodies to soluble protein targets as well as difficult-to-drug G protein-coupled receptors (GPCRs).

Webinar Registration

Dr. Tom Yuan

Sr. Scientist, Antibody Engineering
Twist Biopharma
Dr. Tom Yuan is an antibody engineer at Twist Biopharma. His work focuses on leveraging Twist's DNA-printing technology to design, pan, screen, and characterize synthetic and semi-synthetic antibodies for both client and internal projects. Previously, Tom worked at Surrozen where he discovered and engineered bispecific Wnt agonists.

Dr. Tuval Ben-Yehezkel

CEO
Loop Genomics
Dr. Tuval Ben-Yehezkel earned his PhD at the Weizmann Institute of Science, developing enabling tools and applications in synthetic biology and bioengineering. He helped establish Synvaccine, a synthetic biology start-up. In 2016, he transitioned to Loop Genomics, developing the first fully generic synthetic long-read DNA sequencing platform.
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