Capabilities of the new Twist NGS Methylation Detection System

An end-to-end solution for library preparation, conversion and target enrichment of genomic samples to identify regions of methylation.

Date & Time

April 13, 2021 | 10:30 am SGT

Webinar Description

Twist Bioscience’s proprietary semiconductor-based synthetic DNA manufacturing process featuring a high-throughput silicon platform offers precision at a scale unavailable anywhere else. The innovative method of DNA production enables the manufacture of high-quality synthetic DNA, enabling customers to accelerate success.

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design. Whether you are investigating cellular differentiation or screening liquid biopsies for cancer, the system offers the most efficient methylation detection available.

In this webinar you will learn…

  • Advantages of enzymatic conversion using the unique enzymatic process from New England Biolabs®
  • Benefits of the Twist pre-capture conversion probe design approach
  • Twist NGS Methylation Detection System workflow's applicability to clinically relevant sample types
  • How the workflow leads to increased confidence in methylated-base calls
Webinar Registration


Ananth Bommakanti, Ph.D.
Field Application Scientist, KOSEA | Twist Bioscience

Ananth earned his Ph.D. in Molecular and Cellular Biology from University of Maryland Baltimore. During his tenure as Postdoctoral fellowship at Yale University USA and later at Temasek Life Science Laboratory Singapore, he worked on developing NGS-based diagnostics for early cancer detection assessing radiation poisoning, and biomarker identification for neurological disease progression. He has been with Twist Bioscience for the past 2 years as the regional Bioinformatics and NGS Field Application Scientist helping customers accelerate today’s NGS-based research using Twist range of NGS products.

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