The Good Fight

Precision, Performance and Partnership for Cancer Research Pioneers

The Good Fight means never giving up.

It means working diligently to combat obstacles and seek answers. Not stopping until you’ve done all you could do. It’s partnering with the scientific community as they research the beast we call cancer, with the ultimate goal to eradicate it, or at the very least, prolong the lives of those diagnosed.

This is no easy feat. At Twist, we recognize we are only one part of the very large puzzle, but we know that with our exceptional and consistent performance of our Twist Custom Panels for NGS target enrichment, your research can help to get us one step closer.

Targeted Epigenome Sequencing of cfDNA to Improve Sensitivity for Early Cancer Detection

Gahee Park, PhD shares how DNA Methylation changes are robust cancer-specific markers and how Twist Targeted Methylation solution helped her team achieve higher than previous results — including three times better for enrichment and four times less expensive than other products used previously.

Ultra-Sensitive Residual Leukemia Detection with Patient-Specific Duplex Sequencing

Jesse Salk, PhD explains the challenges of finding a genetic needle in a haystack and shares how Twist's technology and target enrichment solutions help him achieve the otherwise "crazy" results he's seeking from patient samples using duplex sequencing.

Testimonial

“

Twist Custom Panels allowed us to focus on important, medically relevant genes instead of forcing us to work with a whole genome. The panel was concise, with a simple protocol, and the cost reasonable with very good candidate variants already curated by the literature.

”

Researcher studying Childhood Epilepsy

Robust Performance During Multiplex Target Enrichment

Twist Custom Panels deliver high-quality performance across 1-, 8-, and even 16-plex enrichment reactions:

High uniformity for all levels of multiplexing
High on-target rates do not vary with higher levels of multiplexing
Low duplication rates across all levels of multiplexing

The Value of Twist Target Enrichment

Sample to sequencer in a single day

High fidelity dsDNA probes verified by NGS QC

Rapid Customization

From small panels to >1 million probes per pool

Raise Confidence in Variant Detection

Increase coverage depth or run more samples on the same budget