Combinatorial Variant Libraries

Eliminate Bias and Undesirable Motifs

Order Libraries and Get Special Pricing for Clonal Genes!

Unleash the full power of a well-designed library. With Twist Bioscience, you are assured that the library you design contains the specific modifications, exactly where you want them, saving you valuable resources for the downstream screening process.

For now until 31 March, enjoy bundled savings of up to 50% off on subsequent clonal genes order when you purchase Twist CVL. Take advantage of this limited time offer to maximise your budget on both Twist's CVL & Clonal Genes.

Interested in this promotion? Leave your contact details below for us to get back to you. 

Key Benefits

High Diversity Precision

-  Effortlessly incorporate multiple variant domains into one or multiple scaffolds
-  Precise control over codon usage (all 64 codons), amino acid distribution, and length variation

Verified Quality

-  Rigorous quality control, including NGS verification of modified regions
-  Sequence variant ratios documented
-  Uniform distribution of user-defined variants
-  No premature stop codons or unwanted codons

Flexibility

-  Design all sequences, single or multiple domains and combinations - single, pairwise, or triple variants
-  Modular synthesis system enables iteration of future libraries
-  Greater flexibility than TRIM and the degenerate approach

Precision Variant Library Technology Allows for Focused Screening

Twist’s massively parallel silicon-based DNA synthesis platform produces highly uniform and accurate oligos, with 90% of oligos represented within <2.5x of the mean, along with an industry-leading low error rate of 1:2,000 nt.

Combined with our well established molecular biology expertise, the Twist oligo synthesis platform enables the fabrication of highly diverse gene mutant libraries with excellent variant representation and highly specific user-defined composition with no unwanted bias or motifs. Twist library technology enables a comprehensive interrogation of the variant sequence space.

Limited Time Promotion just for you!

For now until 31 March, we are offering 50% off subsequent clonal genes order of up to an order value of the original CVL purchase.

Simply leave your contact information below and we will get back to you soon.


Download Brochure
Library Brochure
Twist’s high-quality libraries make it possible for you to explore a diverse range of potential variants and identify every hit, instead of just a few. Find out more in the brochure.

Combinatorial Variant Libraries Product Sheet
Twist library technology enables a comprehensive interrogation of the variant sequence space. Read the product sheet to learn more.

Watch how Twist's proprietary oligo synthesis technology offers a unique approach to library creation.

Contact Information
Terms & Conditions

1. You must submit your contact information in the form to be entitled for the promotion
2. 50% discount off list price for clonal genes is valid for a single order only, limited to 1 redemption per order
3. Clonal genes discount will be of equal or lower value of the CVL purchase order
4. Promotion is only valid in APAC excluding China and Japan
5. Promotion is only valid until 31 March 2021
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