Advances in cellular reprogramming have opened new doors for studying human cells in health and disease, drug discovery, and the development of cell therapies. Widespread use of human-induced pluripotent stem cell (hiPSC)-derived mature cell types, however, is restricted by complex differentiation protocols and inefficient reprogramming methods.
Bit Bio is developing a platform capable of producing consistent and functional batches every human cell type, with the help of Twist genes.
In this webinar you will:
- Review fundamental concepts of cellular reprogramming.
- Hear how Bit Bio’s novel gene engineering approach, opti-ox™, enables precisely controlled expression of transcription factors, and as a result, deterministic induction of a new cell identity.
- See how Twist’s Clonal Genes and custom vector onboarding have allowed Bit Bio to streamline their molecular cloning of transcription factors required for cellular reprogramming.
- Explore examples of different validated cell models that have been developed using this approach.
