Twist’s Gene Fragments Outperform eBlocks and gBlocks

Accurate fragment synthesis accelerates discovery. Twist Gene Fragments enable you to build more constructs and minimize the time and cost of screening for perfect clones.

Twist’s DNA synthesis technology exhibits extremely low error rates.

In a direct comparison with competitive Gene Fragment products, Twist outperformed with the lowest error rate.
The same sequences were ordered from Twist and Integrated DNA Technologies, Inc. (IDT) for genes of various lengths, and the genes were then cloned and transformed. Colonies were then picked and sequenced using NGS. The data represent the average error rate across the given sequences in each set for Twist Gene Fragments, eBlocks, and gBlocks. The results indicate an average of 2-fold reduction in error rate, or 2-fold greater accuracy in sequence fidelity for Twist Gene Fragments over gBlocks.

Screen Less Discover More

Lower error rates improve your cloning process by minimizing colony screening. With Twist Gene Fragments you should expect to pick 1-2 colonies even for longer genes. This allows you to save time and money by dramatically reducing cloning and sequencing costs. Think bigger, design on a grander scale, and accelerate your discoveries.

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What Scientists Say
The combination of price and service allows us to do science that we could not otherwise do
University of Exeter
The quality has been excellent, and I find that cloning with these genes is successful more often on the first time than with DNA fragments from other companies.
Institute of Systems and Synthetic Biology
The quality of Twist’s gene fragments is so much better than the other vendors I’ve worked with. Their algorithm does a great job of weeding out problematic sequences upfront, so I know I’m going to get a good fragment 99.9% of the time. The customer service is great, and the price is unbeatable.
Oncorus, Inc.
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